Benzeneethanol, β-amino-4-methyl-, (βS)-

Benzeneethanol, β-amino-4-methyl-, (βS)- - Names and Identifiers

Name	(2S)-2-Amino-2-(4-methylphenyl)ethanol
Synonyms	(S)-b-AMino-4-Methyl-benzeneethanol (S)-2-amino-2-(4-methylphenyl)ethanol (2S)-2-Amino-2-(4-methylphenyl)ethanol Benzeneethanol, β-amino-4-methyl-, (βS)- (2S)-2-AMino-2-(4-Methylphenyl)ethan-1-ol (S)-2-AMINO-2-(P-TOLYL)ETHANOL HYDROCHLORIDE (2S)-2-AMINO-2-(4-METHYLPHENYL)ETHAN-1-OL HCl
CAS	327183-90-4
InChI	InChI=1S/C9H13NO/c1-7-2-4-8(5-3-7)9(10)6-11/h2-5,9,11H,6,10H2,1H3/t9-/m1/s1

Benzeneethanol, β-amino-4-methyl-, (βS)- - Physico-chemical Properties

Molecular Formula	C9H13NO
Molar Mass	151.21
Density	1.076±0.06 g/cm3(Predicted)
Boling Point	300.9±27.0 °C(Predicted)
pKa	12.57±0.10(Predicted)
Storage Condition	under inert gas (nitrogen or Argon) at 2–8 °C

Benzeneethanol, β-amino-4-methyl-, (βS)- - Introduction

(2S)-2-Amino-2-(4-methylphenyl)ethanol is an organic compound with the chemical formula C10H15NO. The following is a description of its nature, use, formulation and safety information:

Nature:
-Appearance: colorless liquid
-Melting point: 31-33 ° C
-Boiling point: 279 ° C
-Molecular weight: 165.23g/mol
-Optical activity: It is a chiral compound with optical rotation and positive optical rotation

Use:
- (2S)-2-Amino-2-(4-methylphenyl)ethanol can be used as an intermediate in organic synthesis and can be used to prepare other organic compounds.
-It can also be used in the field of drug synthesis and medicine as the active ingredient of drugs.

Method:
- (2S)-2-Amino-2-(4-methylphenyl)ethanol is prepared by various methods. The following is a common synthetic route:
1. First, 4-methyl anisole was obtained by aromatic substitution reaction using 4-methyl phenol as a raw material.
2. Then, 4-methyl anisole and chloroethane are reacted by acyl chloride to generate the corresponding acyl chloride compound.
3. Finally, through reduction reaction, hydrogen and iron powder are used as reducing agents to reduce the acid chloride compound to (2S)-2-Amino-2-(4-methylphenyl)ethanol.

Safety Information:
- (2S)-2-Amino-2-(4-methylphenyl)ethanol has limited safety data, but according to the general chemical safety precautions, the following guidance should be followed:
-Avoid contact with skin, eyes and respiratory tract, wear protective gloves, goggles and protective masks if necessary.
-Pay attention to fire and explosion-proof measures during operation to avoid contact with open flames and oxidants.
-should be stored in a dry, well-ventilated place, away from easily combustible substances.

Last Update：2024-04-09 21:01:54